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Article

Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants.

Molecular neurobiology - 1 Feb 2014

Wang Shaolin, Yang Zhongli, Ma Jennie Z, Payne Thomas J, Li Ming D

Abstract excerpt

Through linkage analysis, candidate gene approach, and genome-wide association studies (GWAS), many genetic susceptibility factors for substance dependence have been discovered such as the alcohol dehydrogenase gene (ALDH2) for alcohol dependence (AD) and nicotinic acetylcholine receptor (nAChR) subunit variants on chromosomes 8 and 15 for nicotine dependence (ND). However, these confirmed genetic factors...

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Share to ALDH2 gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to High-Throughput Nucleotide Sequencing

Share to Polymorphism, Single Nucleotide

Share to Substance-Related Disorders

Source

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Identifiers

PMID: 23990377
DOI: 10.1007/s12035-013-8541-4
PMCID: PMC3948219

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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