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Article

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.

British journal of cancer - 10 May 2016

Ahmed Mahbubl, Dorling Leila, Kerns Sarah, Fachal Laura, Elliott Rebecca, Partliament Matt, Rosenstein Barry S, Vega Ana, Gómez-Caamaño Antonio, Barnett Gill, Dearnaley David P, Hall Emma, Sydes Matt, Burnet Neil, Pharoah Paul D P, Eeles Ros, West Catharine M L

Abstract excerpt

BACKGROUND: Numerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk have increased toxicity following radiotherapy. METHODS: The study included 1560 prostate cancer patients from four radiotherapy cohorts: RAPPER (n=533), RADIOGEN...

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Identifiers

PMID: 27070714
DOI: 10.1038/bjc.2016.94
PMCID: PMC4865979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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