Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer.

doi:10.1016/j.ebiom.2016.07.022

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Article

Meta-analysis of Genome Wide Association Studies Identifies Genetic Markers of Late Toxicity Following Radiotherapy for Prostate Cancer.

EBioMedicine - 1 Aug 2016

Kerns Sarah L, Dorling Leila, Fachal Laura, Bentzen Søren, Pharoah Paul D P, Barnes Daniel R, Gómez-Caamaño Antonio, Carballo Ana M, Dearnaley David P, Peleteiro Paula, Gulliford Sarah L, Hall Emma, Michailidou Kyriaki, Carracedo Ángel, Sia Michael, Stock Richard, Stone Nelson N, Sydes Matthew R, Tyrer Jonathan P, Ahmed Shahana, Parliament Matthew, Ostrer Harry, Rosenstein Barry S, Vega Ana, Burnet Neil G, Dunning Alison M, Barnett Gillian C, West Catharine M L

Abstract excerpt

Nearly 50% of cancer patients undergo radiotherapy. Late radiotherapy toxicity affects quality-of-life in long-term cancer survivors and risk of side-effects in a minority limits doses prescribed to the majority of patients. Development of a test predicting risk of toxicity could benefit many cancer patients. We aimed to meta-analyze individual level data from four genome-wide association studies from prostate...

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Identifiers

PMID: 27515689
DOI: 10.1016/j.ebiom.2016.07.022
PMCID: PMC5036513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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