Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2016

Dorling Leila, Barnett Gillian C, Michailidou Kyriaki, Coles Charlotte E, Burnet Neil G, Yarnold John, Elliott Rebecca M, Dunning Alison M, Pharoah Paul D P, West Catharine M

Abstract excerpt

PURPOSE: It has been hypothesized that increased predisposition to breast cancer may correlate with radiosensitivity, and thus increased risk of toxicity following breast irradiation. This study investigated the relationship between common breast cancer risk variants and radiotherapy toxicity. EXPERIMENTAL DESIGN: SNP genotypes were determined in female breast cancer patients from the RAPPER (Radiogenomics:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Combined Modality Therapy

Share to Odds Ratio

Share to Radiation Tolerance

Share to Tumor Burden

Source

Open in PubMed Open full text

Identifiers

PMID: 26510858
DOI: 10.1158/1078-0432.CCR-15-1080
PMCID: PMC4751620

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.PMID 26510858Read ↗

No Association Between Polygenic Risk Scores for Cancer and Development of Radiation Therapy Toxicity.Semantic proximity Read ↗

The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.Semantic proximity Read ↗

Common genetic variation associated with increased susceptibility to prostate cancer does not increase risk of radiotherapy toxicity.Semantic proximity Read ↗

Genome-wide association study of treatment-related toxicity two years following radiotherapy for breast cancer.Semantic proximity Read ↗

A genome-wide association study of contralateral breast cancer in the Women's Environmental Cancer and Radiation Epidemiology Study.Semantic proximity Read ↗

Association Between Polymorphisms in DNA Damage Repair Genes and Radiation Therapy-Induced Early Adverse Skin Reactions in a Breast Cancer Population: A Polygenic Risk Score Approach.Semantic proximity Read ↗

The Prediction of Radiotherapy Toxicity Using Single Nucleotide Polymorphism-Based Models: A Step Toward Prevention.Semantic proximity Read ↗

Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study.Semantic proximity Read ↗

Radiogenomics: the search for genetic predictors of radiotherapy response.Semantic proximity Read ↗

A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.Semantic proximity Read ↗

Genetics and genomics of radiotherapy toxicity: towards predictionSemantic proximity Read ↗

Radiogenomics: using genetics to identify cancer patients at risk for development of adverse effects following radiotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.