Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis.

doi:10.1182/blood-2015-10-673095

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Article

Phenotypic, transcriptomic, and genomic features of clonal plasma cells in light-chain amyloidosis.

Blood - 16 Jun 2016

Paiva Bruno, Martinez-Lopez Joaquin, Corchete Luis A, Sanchez-Vega Beatriz, Rapado Inmaculada, Puig Noemi, Barrio Santiago, Sanchez Maria-Luz, Alignani Diego, Lasa Marta, García de Coca Alfonso, Pardal Emilia, Oriol Alberto, Garcia Maria-Esther Gonzalez, Escalante Fernando, González-López Tomás J, Palomera Luis, Alonso José, Prosper Felipe, Orfao Alberto, Vidriales Maria-Belen, Mateos María-Victoria, Lahuerta Juan-Jose, Gutierrez Norma C, San Miguel Jesús F

Abstract excerpt

Immunoglobulin light-chain amyloidosis (AL) and multiple myeloma (MM) are 2 distinct monoclonal gammopathies that involve the same cellular compartment: clonal plasma cells (PCs). Despite the fact that knowledge about MM PC biology has significantly increased in the last decade, the same does not apply for AL. Here, we used an integrative phenotypic, molecular, and genomic approach to study clonal PCs from 24...

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Identifiers

PMID: 27069257
DOI: 10.1182/blood-2015-10-673095

Genes

CDH1
FAS
GLIPR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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