Article
Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis
24 Sept 2004
Abstract excerpt
Immunoglobulin light chain amyloidosis (AL) is characterized by a clonal expansion of plasma cells within the bone marrow. Gene expression analysis was used to identify a unique molecular profile for AL using enriched plasma cells (CD138+) from the bone marrow of 24 patients with AL and 28 patients with multiple myeloma (MM) and 6 healthy controls. Class prediction analysis (PAM) revealed a subset of 12 genes,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
