Article
Fear-of-intimacy-mediated zinc transport controls the function of zinc-finger transcription factors involved in myogenesis.
Development (Cambridge, England) - 1 Jun 2016
Carrasco-Rando Marta, Atienza-Manuel Alexandra, Martín Paloma, Burke Richard, Ruiz-Gómez Mar
Abstract excerpt
Zinc is a component of one-tenth of all human proteins. Its cellular concentration is tightly regulated because its dyshomeostasis has catastrophic health consequences. Two families of zinc transporters control zinc homeostasis in organisms, but there is little information about their specific developmental roles. We show that the ZIP transporter Fear-of-intimacy (Foi) is necessary for the formation of Drosophila...
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