Article
Systematic functional characterization of putative zinc transport genes and identification of zinc toxicosis phenotypes in Drosophila melanogaster.
The Journal of experimental biology - 15 Sept 2012
Lye Jessica C, Richards Christopher D, Dechen Kesang, Paterson David, de Jonge Martin D, Howard Daryl L, Warr Coral G, Burke Richard
Abstract excerpt
The heavy metal zinc is an essential component of the human diet and is incorporated as a structural component in up to 10% of all mammalian proteins. The physiological importance of zinc homeostasis at the cellular level and the molecular mechanisms involved in this process have become topics of increasing interest in recent years. We have performed a systematic functional characterization of the majority of the...
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