Article
Local and systemic effects of targeted zinc redistribution in Drosophila neuronal and gastrointestinal tissues.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine - 1 Dec 2015
Richards Christopher D, Burke Richard
Abstract excerpt
While the effects of systemic zinc ion deficiency and toxicity on animal health are well documented, the impacts of localized, tissue-specific disturbances in zinc homeostasis are less well understood. Previously we have identified zinc dyshomeostasis scenarios caused by the targeted manipulation of zinc transport genes in the Drosophila eye. Over expression of the uptake transporter dZIP42C.1 (dZIP1) combined...
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