Article
The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective.
International journal of molecular sciences - 4 Mar 2016
Kimura Tomoki, Kambe Taiho
Abstract excerpt
Around 3000 proteins are thought to bind zinc in vivo, which corresponds to ~10% of the human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component that functions in numerous physiological processes. It is more widely used as a structural element in proteins than any other transition metal ion, is a catalytic component of many enzymes, and acts as a cellular signaling mediator....
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