Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeted resequencing of regulatory regions at schizophrenia risk loci: Role of rare functional variants at chromatin repressive states.

Schizophrenia research - 1 Jul 2016

González-Peñas Javier, Amigo Jorge, Santomé Luis, Sobrino Beatriz, Brenlla Julio, Agra Santiago, Paz Eduardo, Páramo Mario, Carracedo Ángel, Arrojo Manuel, Costas Javier

Abstract excerpt

There is mounting evidence that regulatory variation plays an important role in genetic risk for schizophrenia. Here, we specifically search for regulatory variants at risk by sequencing promoter regions of twenty-three genes implied in schizophrenia by copy number variant or genome-wide association studies. After strict quality control, a total of 55,206bp per sample were analyzed in 526 schizophrenia cases and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Assembly and Disassembly
Share to Chromatin Immunoprecipitation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryonic Stem Cells

Share to Epigenomics

Share to Genetic Loci

Share to Hepatocyte Nuclear Factor 1-beta

Share to LIM-Homeodomain Proteins

Share to Regulatory Sequences, Nucleic Acid

Source

Identifiers

PMID: 27066855
DOI: 10.1016/j.schres.2016.03.029

Genes

LHX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeted resequencing of regulatory regions at schizophrenia risk loci: Role of rare functional variants at chromatin repressive states.PMID 27066855Read ↗

Molecular regulatory mechanisms of schizophrenia-associated functional non-coding variants.Semantic proximity Read ↗

Regulome-wide association study identifies enhancer properties associated with risk for schizophreniaSemantic proximity Read ↗

Rare schizophrenia risk variants are enriched in genes shared with neurodevelopmental disordersSemantic proximity Read ↗

Use of the epigenetic toolbox to contextualize common variants associated with schizophrenia risk .Semantic proximity Read ↗

Convergence of the dysregulated regulome in schizophrenia with polygenic risk and evolutionarily constrained enhancers.Semantic proximity Read ↗

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal developmentSemantic proximity Read ↗

Systematic investigation of allelic regulatory activity of schizophrenia-associated common variantsSemantic proximity Read ↗

Evaluation of Chromatin Accessibility in Prefrontal Cortex of Schizophrenia Cases and ControlsSemantic proximity Read ↗

De novo mutations in schizophrenia implicate chromatin remodeling and support a genetic overlap with autism and intellectual disability.Semantic proximity Read ↗

Cell-specific histone modification maps in the human frontal lobe link schizophrenia risk to the neuronal epigenome.Semantic proximity Read ↗

The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal developmentSemantic proximity Read ↗

[A role of transcription factors in pathogenic processes associated with schizophrenia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.