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[A role of transcription factors in pathogenic processes associated with schizophrenia].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 2024

Karpov D S, Marilovtseva E V, Golimbet V E

Abstract excerpt

Schizophrenia is a severe mental illness, the etiology and pathogenesis of which are significantly contributed by hereditary factors. Genome-wide association analysis shows that the majority of genetic variants associated with a high risk of schizophrenia are located in regulatory regions of genes. In this brief review, data on the overall structure of the major regulatory regions of genes are summarized. The...

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PMID: 39690551
DOI: 10.17116/jnevro202412411149

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