Article
Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities.
Chemosphere - 1 Nov 2015
Gómez-Martín Antonio, Hernández Antonio F, Martínez-González Luis Javier, González-Alzaga Beatriz, Rodríguez-Barranco Miguel, López-Flores Inmaculada, Aguilar-Garduno Clemente, Lacasana Marina
Abstract excerpt
Polymorphisms in genes encoding xenobiotic-metabolizing enzymes (XME) are important parameters accounting for the wide inter-individual variability to environmental exposures. Paraoxonase-1 (PON1), butyrylcholinesterase (BChE) and Cytochrome-P450 constitute major classes of XME involved in the detoxification of pesticide chemicals, in particular organophosphates. This study explored the allelic frequency, linkage...
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