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Article

Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations.

World journal of gastroenterology - 7 Jan 2015

Cevik Dilek, Yildiz Gokhan, Ozturk Mehmet

Abstract excerpt

AIM: To determine the mutation status of human telomerase reverse transcriptase gene (TERT) promoter region in hepatocellular carcinoma (HCC) from different geographical regions. METHODS: We analyzed the genomic DNA sequences of 59 HCC samples comprising 15 cell lines and 44 primary tumors, collected from patients living in Asia, Europe and Africa. We amplified a 474 bp DNA fragment of the promoter region of TERT...

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Identifiers

PMID: 25574106
DOI: 10.3748/wjg.v21.i1.311
PMCID: PMC4284350

Genes

TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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