Article
Clinicopathological characteristics of TERT promoter mutation and telomere length in hepatocellular carcinoma.
Medicine - 1 Feb 2017
Lee Hye Won, Park Tae In, Jang Se Young, Park Soo Young, Park Won-Jin, Jung Soo-Jung, Lee Jae-Ho
Abstract excerpt
Promoter mutations in telomerase reverse transcriptase (TERT) and telomere length have been studied in various tumors. In the present study, the frequency and clinical characteristics of TERT promoter mutation and telomere length were studied in hepatocellular carcinoma (HCC). TERT promoter mutation and telomere length were analyzed in 162 tumor samples of the patients with HCC by sequencing and real-time PCR,...
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