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Article

Telomerase reverse transcriptase (TERT) promoter mutation correlated with intratumoral heterogeneity in hepatocellular carcinoma.

Pathology international - 1 Sept 2020

Kwa Wit Thun, Effendi Kathryn, Yamazaki Ken, Kubota Naoto, Hatano Mami, Ueno Akihisa, Masugi Yohei, Sakamoto Michiie

Abstract excerpt

Telomerase reverse transcriptase (TERT) promoter mutations are frequently observed in hepatocellular carcinoma (HCC); however, the impact of TERT promoter mutations (TPMs) on clinical features and morphological patterns in HCC remains unresolved. Using DNA extracted from 97 HCCs, correlations between TPM status and both the clinical features of HCC and the immunohistochemically-based subgroups were evaluated....

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Identifiers

PMID: 32559017
DOI: 10.1111/pin.12974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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