Article
Effects of HLA-DRB1/DQB1 Genetic Variants on Neuroimaging in Healthy, Mild Cognitive Impairment, and Alzheimer's Disease Cohorts.
Molecular neurobiology - 1 Jul 2017
Wang Zi-Xuan, Wang Hui-Fu, Tan Lin, Liu Jinyuan, Wan Yu, Sun Fu-Rong, Tan Meng-Shan, Tan Chen-Chen, Jiang Teng, Tan Lan, Yu Jin-Tai
Abstract excerpt
Alzheimer's disease (AD) is the most common form of dementia and exhibits a considerable level of heritability. Previous association studies gave evidence for the associations of HLA-DRB1/DQB1 alleles with AD. However, how and when the gene variants in HLA-DRB1/DQB1 function in AD pathogenesis has yet to be determined. Here, we firstly investigated the association of gene variants in HLA-DRB1/DQB1 alleles and AD...
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