Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.

doi:10.1016/j.neurobiolaging.2014.12.028

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Article

Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.

Neurobiology of aging - 1 Apr 2015

Chauhan Ganesh, Adams Hieab H H, Bis Joshua C, Weinstein Galit, Yu Lei, Töglhofer Anna Maria, Smith Albert Vernon, van der Lee Sven J, Gottesman Rebecca F, Thomson Russell, Wang Jing, Yang Qiong, Niessen Wiro J, Lopez Oscar L, Becker James T, Phan Thanh G, Beare Richard J, Arfanakis Konstantinos, Fleischman Debra, Vernooij Meike W, Mazoyer Bernard, Schmidt Helena, Srikanth Velandai, Knopman David S, Jack Clifford R, Amouyel Philippe, Hofman Albert, DeCarli Charles, Tzourio Christophe, van Duijn Cornelia M, Bennett David A, Schmidt Reinhold, Longstreth William T, Mosley Thomas H, Fornage Myriam, Launer Lenore J, Seshadri Sudha, Ikram M Arfan, Debette Stephanie

Abstract excerpt

Whether novel risk variants of Alzheimer's disease (AD) identified through genome-wide association studies also influence magnetic resonance imaging-based intermediate phenotypes of AD in the general population is unclear. We studied association of 24 AD risk loci with intracranial volume, total brain volume, hippocampal volume (HV), white matter hyperintensity burden, and brain infarcts in a meta-analysis of...

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PMID: 25670335
DOI: 10.1016/j.neurobiolaging.2014.12.028
PMCID: PMC4391343

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APOE
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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