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Article

Genetic Association of HLA Gene Variants with MRI Brain Structure in Alzheimer's Disease.

Molecular neurobiology - 1 Jul 2017

Wang Zi-Xuan, Wan Yu, Tan Lin, Liu Jinyuan, Wang Hui-Fu, Sun Fu-Rong, Tan Meng-Shan, Tan Chen-Chen, Jiang Teng, Tan Lan, Yu Jin-Tai

Abstract excerpt

There is accumulating evidence that the human leukocyte antigen (HLA) gene variants are associated with Alzheimer's disease (AD). However, how they affect AD occurrence is still unknown. In this study, we firstly investigated the association of gene variants in HLA gene variants and brain structures on MRI in a large sample from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to explore the effects of HLA...

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Source

Identifiers

PMID: 27056077
DOI: 10.1007/s12035-016-9889-z

Genes

HFE
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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