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Article

The genetic architecture of substance use and its diverse correlations with mental health traits.

Psychiatry research - 1 Dec 2024

Wormington Briar, Thorp Jackson G, Gerring Zachary F, Scott James G, Akosile Wole, Derks Eske M

Abstract excerpt

Although harmful substance use is common and represented by shared symptom features and high genetic correlations, the underlying genetic relationships between substance use traits have not been fully explored. We have investigated the genetic architecture of substance use traits through exploratory and confirmatory factor analyses using genomic structural equation modeling (Genomic SEM), and explored genetic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39307107
DOI: 10.1016/j.psychres.2024.116200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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