Article
COMT Val(158)Met genotype and cannabis use in people with an At Risk Mental State for psychosis: Exploring Gene x Environment interactions.
Schizophrenia research - 1 Jul 2016
Nieman Dorien H, Dragt Sara, van Duin Esther D A, Denneman Nadine, Overbeek Jozefien M, de Haan Lieuwe, Rietdijk Judith, Ising Helga K, Klaassen Rianne M C, van Amelsvoort Thérèse, Wunderink Lex, van der Gaag Mark, Linszen Don H
Abstract excerpt
BACKGROUND: Epidemiological and retrospective studies suggest a cannabis x catechol-O-methyltransferase (COMT) Val(158)Met interaction effect on development of psychosis. The aim of this study was to examine this interaction and its association with severity of subclinical symptoms in people with an At Risk Mental State (ARMS) for psychosis. METHODS: Severity of symptoms, cannabis use and genotype were assessed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.