PTPN22 is not associated with Behçet's disease. Study spanning the complete gene region in the Spanish population and meta-analysis of the functional variant R620W.

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PTPN22 is not associated with Behçet's disease. Study spanning the complete gene region in the Spanish population and meta-analysis of the functional variant R620W.

Clinical and experimental rheumatology - 1 Jan 2000

Ortiz-Fernández Lourdes, Montes-Cano Marco Antonio, García-Lozano José-Raúl, Conde-Jaldón Marta, Ortego-Centeno Norberto, González-Leon Rocio, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá Maria Rosa, Solans Roser, Blanco Ricardo, Barnosi-Marín Ana-Celia, Fanlo Patricia, Rodríguez Carballeira Monica, Camps Maria Teresa, Castañeda Santos, Martín Javier, González-Escribano María Francisca

Abstract excerpt

OBJECTIVES: The functional variant R620W of the protein tyrosine phosphatase non receptor-22 (PTPN22) gene plays an important role in susceptibility to several immuno-mediated pathologies. Behçet's disease (BD) is a complex disease related to the immune system with a demonstrated genetic base. The HLA class I genes are the most important genetic factors in BD although other genes are also involved in the...

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PMID: 27050764

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PTPN22

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PTPN22 is not associated with Behçet's disease. Study spanning the complete gene region in the Spanish population and meta-analysis of the functional variant R620W.PMID 27050764Read ↗

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