Article
Interleukin-21 receptor gene polymorphism (rs2285452 A/G) is associated with susceptibility to Behçet's disease.
International journal of immunogenetics - 1 Aug 2023
Lahmar Rajaa, Chabchoub Elyes, Zemni Ramzi, Anis Mzabi, Ghannouchi Neirouz, Slama Foued Ben Hadj
Abstract excerpt
Behçet's disease (BD) is a chronic auto inflammatory disorder of unknown aetiology. Recently, the dysregulation of interleukin-21 receptor (IL-21R) has been incriminated in different autoimmune and auto-inflammatory diseases, such as systemic lupus erythematous, rheumatoid arthritis, and type 1 diabetes. Herein, we aimed to investigate the association of two Il-21R gene polymorphisms with BD. IL-21R rs2214537 and...
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