Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of the PTPN22 620W polymorphism with Behcet's disease.

Annals of the rheumatic diseases - 1 Nov 2007

Baranathan Vijay, Stanford Miles R, Vaughan Robert W, Kondeatis Elli, Graham Elizabeth, Fortune Farida, Madanat Wafa, Kanawati Charlie, Ghabra Marwen, Murray Philip I, Wallace Graham R

Abstract excerpt

OBJECTIVES: A single nucleotide polymorphism (SNP) of the gene encoding protein tyrosine phosphatase type 22 (PTPN22 620W) has recently been described as a strong common genetic risk factor for human autoimmune disease. We have analysed the association of PTPN22 620W in patients with Behçet's disease (BD). METHODS: Genomic DNA was obtained from 270 patients with BD from the UK and the Middle East. Normal controls...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Arabs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Behcet Syndrome

Share to Gene Frequency

Share to Middle East

Share to Polymorphism, Single Nucleotide

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 22

Share to Protein Tyrosine Phosphatases

Source

Open in PubMed Open full text

Identifiers

PMID: 17660222
DOI: 10.1136/ard.2007.073866
PMCID: PMC2111602

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of the PTPN22 620W polymorphism with Behcet's disease.PMID 17660222Read ↗

PTPN22 gene polymorphism in Behçet's disease.Semantic proximity Read ↗

Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease.Semantic proximity Read ↗

PTPN22 is not associated with Behçet's disease. Study spanning the complete gene region in the Spanish population and meta-analysis of the functional variant R620W.Semantic proximity Read ↗

[Relevance of the gene variant PTPN22 620W for rheumatology].Semantic proximity Read ↗

Protein tyrosine phosphatase non-receptor type 2 (PTPN2) gene polymorphisms (rs2542151, rs7234029) in Egyptian Behçet's disease patients: a preliminary report.Semantic proximity Read ↗

The PTPN22 620W allele is a risk factor for Wegener's granulomatosis.Semantic proximity Read ↗

The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease.Semantic proximity Read ↗

Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus.Semantic proximity Read ↗

No association of PTPN22 polymorphisms with susceptibility to ocular Behcet's disease in two Chinese Han populations.Semantic proximity Read ↗

Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.Semantic proximity Read ↗

Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.Semantic proximity Read ↗

PTPN22: setting thresholds for autoimmunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.