Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

doi:10.1371/journal.pone.0161305

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Article

Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

PloS one - 1 Jan 2016

Ortiz-Fernández Lourdes, Carmona Francisco-David, Montes-Cano Marco-Antonio, García-Lozano José-Raúl, Conde-Jaldón Marta, Ortego-Centeno Norberto, Castillo María Jesús, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá María Rosa, Solans Roser, Blanco Ricardo, Barnosi-Marín Ana-Celia, Gómez de la Torre Ricardo, Fanlo Patricia, Rodríguez-Carballeira Mónica, Rodríguez-Rodríguez Luis, Camps Teresa, Castañeda Santos, Alegre-Sancho Juan-Jose, Martín Javier, González-Escribano María Francisca

Abstract excerpt

Behcet's disease (BD) is an immuno-mediated vasculitis in which knowledge of its etiology and genetic basis is limited. To improve the current knowledge, a genetic analysis performed with the Immunochip platform was carried out in a population from Spain. A discovery cohort comprising 278 BD cases and 1,517 unaffected controls were genotyped using the Immunochip platform. The validation step was performed on an...

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PMID: 27548383
DOI: 10.1371/journal.pone.0161305
PMCID: PMC4993481

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CNTN5
JRKL

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