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Article

Association of genetic variations in PTPN2 and CD122 with ocular Behcet's disease.

The British journal of ophthalmology - 1 Jul 2018

Zhang Qi, Li Hua, Hou Shengping, Yu Hongsong, Su Guannan, Deng Bolin, Qi Jian, Zhou Chunjiang, Kijlstra Aize, Yang Peizeng

Abstract excerpt

BACKGROUND: Protein tyrosine phosphatases (PTPs) play critical roles in human autoimmunity. Previous studies found that PTPN2 may be the key regulatory factor in the T-cell-mediated immune response. PTPN2 regulates the Janus kinase/signal transducers and activators of transcription pathway by inhibiting signalling via the interleukin (IL)-2 receptor (CD122). An association between genetic variations in PTPN2 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme-Linked Immunosorbent Assay

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Source

Identifiers

PMID: 29502070
DOI: 10.1136/bjophthalmol-2017-310820

Genes

PTPN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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