Article
PTPN2 rs1893217 single-nucleotide polymorphism is associated with risk of Behçet's disease in a Chinese Han population.
Clinical and experimental rheumatology - 1 Jan 2000
Wu Ziyan, Chen Hua, Sun Fei, Xu Juanjuan, Zheng Wenjie, Li Ping, Chen Si, Shen Ming, Zhang Wen, Li Mengtao, You Xin, Wu Qingjun, Zhang Fengchun, Li Yongzhe
Abstract excerpt
OBJECTIVES: Behçet's disease (BD) is a rare, chronic, relapsing, systemic, immune-mediated vasculitis and the etiology remains to be defined. This study investigated single-nucleotide polymorphisms (SNP) of tyrosine-protein phosphatase non-receptor type 2 (PTPN2) and inducible T-cell co-stimulator-ligand gene (ICOSLG) in Chinese Han BD patients and healthy controls because SNPs of these two genes are associated...
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