Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene mutations in chronic lymphocytic leukemia.

Seminars in oncology - 1 Apr 2016

Amin Nisar A, Malek Sami N

Abstract excerpt

The recent discovery of genes mutated in chronic lymphocytic leukemia (CLL) has stimulated new research into the role of these genes in CLL pathogenesis. CLL cases carry approximately 5-20 mutated genes per exome, a lower number than detected in many human tumors. Of the recurrently mutated genes in CLL, all are mutated in 10% or less of patients when assayed in unselected CLL cohorts at diagnosis. Mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transformation, Neoplastic
Share to Clonal Evolution
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

Share to Genetic Association Studies

Share to Hematopoietic Stem Cells

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Mutation Rate

Source

Identifiers

PMID: 27040699
DOI: 10.1053/j.seminoncol.2016.02.002

Genes

NOTCH1
ZAP70

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene mutations in chronic lymphocytic leukemia.PMID 27040699Read ↗

The clinical implications of gene mutations in chronic lymphocytic leukaemia.Semantic proximity Read ↗

Recurrent gene mutations in CLL.Semantic proximity Read ↗

Gene Mutations and Treatment Outcome in Chronic Lymphocytic Leukemia: Results From the CLL8 TrialSemantic proximity Read ↗

Molecular genetics of high-risk chronic lymphocytic leukemia.Semantic proximity Read ↗

Novel prognostic gene mutations identified in chronic lymphocytic leukemia and their impact on clinical practice.Semantic proximity Read ↗

Importance of genetics in chronic lymphocytic leukemia.Semantic proximity Read ↗

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.Semantic proximity Read ↗

The mutational landscape of chronic lymphocytic leukemia and its impact on prognosis and treatmentSemantic proximity Read ↗

Genetic Abnormalities in Chronic Lymphocytic Leukemia: Where We Are and Where We GoSemantic proximity Read ↗

ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-2024 update.Semantic proximity Read ↗

Mutations in chronic lymphocytic leukemia and how they affect therapy choice: focus on NOTCH1, SF3B1, and TP53.Semantic proximity Read ↗

[The genetic landscape of chronic lymphocytic leukemia].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.