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Article

The clinical implications of gene mutations in chronic lymphocytic leukaemia.

British journal of cancer - 12 Apr 2016

Rossi Davide, Gaidano Gianluca

Abstract excerpt

Chronic lymphocytic leukaemia (CLL) is a molecularly heterogeneous disease as revealed by recent genomic studies. Among genetic lesions that are recurrent in CLL, few clinically validated prognostic markers, such as TP53 mutations and 17p deletion, are available for the use in clinical practice to guide treatment decisions. Recently, several novel molecular markers have been identified in CLL. Though these...

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Share to Chronic Lymphocytic Leukemia Research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunodeficiency and Autoimmune Disorders

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Tumor Suppressor Protein p53

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Identifiers

PMID: 27031852
DOI: 10.1038/bjc.2016.78
PMCID: PMC4984803

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