Article
Novel prognostic gene mutations identified in chronic lymphocytic leukemia and their impact on clinical practice.
Clinical lymphoma, myeloma & leukemia - 1 Aug 2014
Campregher Paulo Vidal, Hamerschlak Nelson
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is a lymphoid malignancy characterized by progressive accumulation of mature lymphocytes in the peripheral blood, bone marrow, liver, and lymphoid organs. Although most patients with CLL have an insidious clinical course, a subset of cases present with fast evolution and chemotherapy resistance, leading to high morbidity and mortality. Few clinically validated prognostic...
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