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Article

Female-favorable attenuation of coronary myogenic constriction via reciprocal activations of epoxyeicosatrienoic acids and nitric oxide.

American journal of physiology. Heart and circulatory physiology - 1 Jun 2016

Froogh Ghezal, Qin Jun, Kandhi Sharath, Le Yicong, Jiang Houli, Luo Meng, Sun Dong, Huang An

Abstract excerpt

Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid via CYP/epoxygenases, which are catabolized by soluble epoxide hydrolase (sEH) and known to possess cardioprotective properties. To date, the role of sEH in the modulation of pressure-induced myogenic response/constriction in coronary arteries, an important regulatory mechanism in the coronary circulation, and the issue as to whether the...

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Identifiers

PMID: 27016584
DOI: 10.1152/ajpheart.00906.2015
PMCID: PMC4935517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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