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Article

Connexin 43 Plays a Role in Pulmonary Vascular Reactivity in Mice.

International journal of molecular sciences - 27 Jun 2018

Htet Myo, Nally Jane E, Shaw Andrew, Foote Bradley E, Martin Patricia E, Dempsie Yvonne

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a chronic condition characterized by vascular remodeling and increased vaso-reactivity. PAH is more common in females than in males (~3:1). Connexin (Cx)43 has been shown to be involved in cellular communication within the pulmonary vasculature. Therefore, we investigated the role of Cx43 in pulmonary vascular reactivity using Cx43 heterozygous (Cx43+/−) mice and...

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Source

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Identifiers

PMID: 29954114
DOI: 10.3390/ijms19071891
PMCID: PMC6073802

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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