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Article

Cytochrome P450-derived eicosanoids and vascular dysfunction in coronary artery disease patients.

Atherosclerosis - 1 Apr 2013

Schuck Robert N, Theken Katherine N, Edin Matthew L, Caughey Melissa, Bass Almasa, Ellis Kyle, Tran Bryant, Steele Savanna, Simmons Brian P, Lih Fred B, Tomer Kenneth B, Wu Michael C, Hinderliter Alan L, Stouffer George A, Zeldin Darryl C, Lee Craig R

Abstract excerpt

OBJECTIVE: Accumulating preclinical and epidemiologic evidence has emerged to suggest that modulation of cytochrome P450 (CYP)-mediated eicosanoid metabolism may be a viable vascular protective therapeutic strategy for the secondary prevention of coronary artery disease (CAD). The functional relationship between CYP-derived eicosanoid metabolite levels and vascular dysfunction in humans with established CAD,...

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Source

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Identifiers

PMID: 23466098
DOI: 10.1016/j.atherosclerosis.2013.01.034
PMCID: PMC3638946

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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