Article

Increased endothelium activation and leakage do not promote diastolic dysfunction in mice fed with a high fat diet and treated with L-NAME

2023-02-08

Abstract excerpt

Coronary microvascular disease has been proposed to be responsible for heart failure with preserved ejection fraction (HFpEF) about 10 years ago. However, to date the role and phenotype of the coronary microvasculature has still been poorly considered and investigated in animal models of HFpEF. <h4>Objective</h4> To determine whether endothelial dysfunction participates in the development of diastolic dysfunction...

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Literature Corpus work: 81ea9daa-8b3f-52f8-ad46-2d8bb8a47c3f
DOI: 10.1101/2023.02.08.527684

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