Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk.

Neuropsychobiology - 1 Jan 2016

Kwiatkowski Dominik, Czarny Piotr, Toma Monika, Korycinska Anna, Sowinska Katarzyna, Galecki Piotr, Bachurska Agnieszka, Bielecka-Kowalska Anna, Szemraj Janusz, Maes Michael, Sliwinski Tomasz

Abstract excerpt

BACKGROUND: One of the factors that contribute to Alzheimer's disease (AD) is the DNA damage caused by oxidative stress and inflammation that occurs in nerve cells. It has been suggested that the risk of AD may be associated with an age-dependent reduction of the DNA repair efficiency. Base excision repair (BER) is, among other things, a main repair system of oxidative DNA damage. One of the reasons for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-(Apurinic or Apyrimidinic Site) Lyase
Share to DNA Glycosylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Ligase ATP

Share to DNA Ligases

Share to Flap Endonucleases

Share to Poly-ADP-Ribose Binding Proteins

Share to Xenopus Proteins

Source

Identifiers

PMID: 27010693
DOI: 10.1159/000444643

Genes

LIG1
LIG3
APEX1
FEN1
NEIL1
OGG1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk.PMID 27010693Read ↗

Variants of Base Excision Repair Genes MUTYH , PARP1 and XRCC1 in Alzheimer's Disease Risk.Semantic proximity Read ↗

Single nucleotide polymorphisms in base-excision repair genes hOGG1, APE1 and XRCC1 do not alter risk of Alzheimer's disease.Semantic proximity Read ↗

Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer's Disease Risk.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms in Base-Excision Repair-Related Genes Involved in the Risk of an Occurrence of Non-Alcoholic Fatty Liver Disease.Semantic proximity Read ↗

DNA repair gene OGG1 polymorphism and its relation with oxidative DNA damage in patients with Alzheimer’s diseaseSemantic proximity Read ↗

Altered DNA base excision repair profile in brain tissue and blood in Alzheimer’s diseaseSemantic proximity Read ↗

Link of BIN1, CLU, and IDE Gene Polymorphisms with the Susceptibility of Alzheimer's Disease: Evidence from a Meta-analysis.Semantic proximity Read ↗

Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder.Semantic proximity Read ↗

Association of APEX1 and OGG1 gene polymorphisms with breast cancer risk among Han women in the Gansu Province of China.Semantic proximity Read ↗

Genetic variants in the DNA repair gene NEIL3 and the risk of myocardial infarction in a nested case-control study. The HUNT Study.Semantic proximity Read ↗

Genetic variation in the base excision repair pathway and bladder cancer risk.Semantic proximity Read ↗

BIN1 gene rs744373 polymorphism contributes to Alzheimer's disease in East Asian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.