Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variants of Base Excision Repair Genes MUTYH , PARP1 and XRCC1 in Alzheimer's Disease Risk.

Neuropsychobiology - 1 Jan 2015

Kwiatkowski Dominik, Czarny Piotr, Galecki Piotr, Bachurska Agnieszka, Talarowska Monika, Orzechowska Agata, Bobińska Kinga, Bielecka-Kowalska Anna, Pietras Tadeusz, Szemraj Janusz, Maes Michael, Sliwinski Tomasz

Abstract excerpt

BACKGROUND: Many clinical studies have shown that oxidative stress pathways and the efficiency of the oxidative DNA damage base excision repair (BER) system are associated with the pathogenesis of Alzheimer's disease (AD). Reduced BER efficiency may result from polymorphisms of BER-related genes. In the present study, we examine whether single nucleotide polymorphisms (SNPs) of BER genes are associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to DNA Glycosylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Models, Molecular

Share to Odds Ratio

Share to Poly (ADP-Ribose) Polymerase-1

Share to Poly(ADP-ribose) Polymerases

Share to X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 25998844
DOI: 10.1159/000381985

Genes

PARP1
XRCC1
MUTYH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variants of Base Excision Repair Genes MUTYH , PARP1 and XRCC1 in Alzheimer's Disease Risk.PMID 25998844Read ↗

Associations between DNA Damage, DNA Base Excision Repair Gene Variability and Alzheimer's Disease Risk.Semantic proximity Read ↗

Altered DNA base excision repair profile in brain tissue and blood in Alzheimer’s diseaseSemantic proximity Read ↗

Single nucleotide polymorphisms in base-excision repair genes hOGG1, APE1 and XRCC1 do not alter risk of Alzheimer's disease.Semantic proximity Read ↗

Association between Single-Nucleotide Polymorphisms of the hOGG1,NEIL1,APEX1, FEN1,LIG1, and LIG3 Genes and Alzheimer's Disease Risk.Semantic proximity Read ↗

Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance.Semantic proximity Read ↗

DNA damage and repair in Alzheimer's disease.Semantic proximity Read ↗

DNA base excision repair gene polymorphisms modulate human cognitive performance and decline during normal life span.Semantic proximity Read ↗

The Arg194Trp polymorphism in DNA repair gene XRCC1 and the risk for sporadic late-onset Alzheimer's disease.Semantic proximity Read ↗

Contributions of DNA Damage to Alzheimer’s DiseaseSemantic proximity Read ↗

DNA repair gene OGG1 polymorphism and its relation with oxidative DNA damage in patients with Alzheimer’s diseaseSemantic proximity Read ↗

Evaluation of the poly(ADP-ribose) polymerase-1 gene variants in Alzheimer's disease.Semantic proximity Read ↗

Selected polymorphisms of base excision repair genes and pancreatic cancer risk in Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.