Article
Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
Age (Dordrecht, Netherlands) - 1 Apr 2016
Nettiksimmons Jasmine, Tranah Gregory, Evans Daniel S, Yokoyama Jennifer S, Yaffe Kristine
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in and near ABCA7, BIN1, CASS4, CD2AP, CD33, CELF1, CLU, complement receptor 1 (CR1), EPHA1, EXOC3L2, FERMT2, HLA cluster (DRB5-DQA), INPP5D, MEF2C, MS4A cluster (MS4A3-MS4A6E), NME8, PICALM, PTK2B, SLC24A4, SORL1, and ZCWPW1 have been associated with Alzheimer's disease (AD) in large meta-analyses. We aimed to determine whether established AD-associated genes are associated...
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