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Article

FOXP3+Helios+ Regulatory T Cells, Immune Activation, and Advancing Disease in HIV-Infected Children.

Journal of acquired immune deficiency syndromes (1999) - 15 Aug 2016

Khaitan Alka, Kravietz Adam, Mwamzuka Mussa, Marshed Fatma, Ilmet Tiina, Said Swalehe, Ahmed Aabid, Borkowsky William, Unutmaz Derya

Abstract excerpt

Regulatory T cells (Tregs) are functionally suppressive CD4 T cells, critical for establishing peripheral tolerance and controlling inflammatory responses. Previous reports of Tregs during chronic HIV disease have conflicting results with higher or lower levels compared with controls. Identifying true Tregs with suppressive activity proves challenging during HIV infection, as traditional Treg markers, CD25 and...

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Identifiers

PMID: 27003495
DOI: 10.1097/QAI.0000000000001000
PMCID: PMC4942350

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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