Article
Impaired Phenotype and Function of T Follicular Helper Cells in HIV-1-Infected Children Receiving ART.
Medicine - 1 Jul 2015
Bekele Yonas, Amu Sylvie, Bobosha Kidist, Lantto Rebecka, Nilsson Anna, Endale Birtukan, Gebre Meseret, Aseffa Abraham, Rethi Bence, Howe Rawleigh, Chiodi Francesca
Abstract excerpt
T follicular helper (Tfh) cells are important components in development of specific humoral immune responses; whether the number and biology of Tfh cells is impaired in HIV-1-infected children is not yet studied.The frequency, phenotype, and function of Tfh cells and B cells were determined in blood of HIV-1-infected children receiving antiretroviral therapy (ART) and age-matched controls. Flow cytometry was used...
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