Article
Homeostasis and function of regulatory T cells in HIV/SIV infection.
Journal of virology - 1 Oct 2012
Moreno-Fernandez Maria E, Presicce Pietro, Chougnet Claire A
Abstract excerpt
Regulatory T cells (Tregs) play a pivotal role in the maintenance of tolerance as well as in the control of immune activation, particularly during chronic infections. In the setting of HIV infection, the majority of studies have reported an increase in Treg frequency but a decrease in absolute number in all immune compartments of HIV-infected individuals. Several nonexclusive mechanisms have been postulated to...
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