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Article

Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy.

PloS one - 1 Jan 2011

Presicce Pietro, Orsborn Kris, King Eileen, Pratt Jesse, Fichtenbaum Carl J, Chougnet Claire A

Abstract excerpt

Regulatory T cells (Tregs) act by suppressing the activation and effector functions of innate and adaptive immune responses. HIV infection impacts Treg proportion and phenotype, although discrepant results have been reported depending on the patient population and the way Tregs were characterized. The effects of highly active antiretroviral therapy (HAART) on Treg frequency have not been thoroughly documented. We...

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Identifiers

PMID: 22162758
DOI: 10.1371/journal.pone.0028118
PMCID: PMC3230597

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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