Article
A genome-wide high-resolution array-CGH analysis of cutaneous melanoma and comparison of array-CGH to FISH in diagnostic evaluation.
The Journal of molecular diagnostics : JMD - 1 Sept 2013
Wang Lu, Rao Mamta, Fang Yuqiang, Hameed Meera, Viale Agnes, Busam Klaus, Jhanwar Suresh C
Abstract excerpt
Benign melanocytic nevi and cutaneous melanomas can be difficult to differentiate by means of routine microscopic analysis. Recent evidence has suggested that cytogenomic analysis may be a useful diagnostic method for evaluation of melanocytic proliferations. We investigated the array-based comparative genomic hybridization (aCGH) platform for DNA copy number analysis of formalin-fixed, paraffin-embedded (FFPE)...
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