Article
DNA copy number changes correlate with clinical behavior in melanocytic neoplasms: proposal of an algorithmic approach.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2020
Alomari Ahmed K, Miedema Jayson R, Carter Michael D, Harms Paul W, Lowe Lori, Durham Alison B, Fullen Douglas R, Patel Rajiv M, Hristov Alexandra C, Chan May P, Wang Min, Andea Aleodor A
Abstract excerpt
Increasingly, molecular methods are being utilized in the workup of melanocytic neoplasms. To this end, we sought to correlate data from a single nucleotide polymorphism (SNP) array platform based on molecular inversion probes with clinical data. Copy number variation (CNV) data were obtained on 95 melanocytic tumors (6 ordinary nevi, 15 atypical nevi, 34 ambiguous neoplasms, and 40 melanomas) from 92 patients....
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