Article

Copy Number Analysis in Congenital Nevi: Concordance and Diagnostic Limitations of aCGH, sWGS, and Methylation Profiling

2026-03-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Distinguishing benign proliferative nodules (PNs) from melanoma arising within congenital melanocytic nevi remains a major diagnostic challenge. Copy number alteration (CNA) analysis is widely used to support classification, but current criteria were developed using array comparative genomic hybridization (aCGH). The performance of alternative platforms such as shallow whole...

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Literature Corpus work: f59c3587-2b4b-5154-9799-8ec7d4c74c01
DOI: 10.64898/2026.03.03.26347388

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