Article
HRR25, a putative protein kinase from budding yeast: association with repair of damaged DNA.
Science (New York, N.Y.) - 30 Aug 1991
Hoekstra M F, Liskay R M, Ou A C, DeMaggio A J, Burbee D G, Heffron F
Abstract excerpt
In simple eukaryotes, protein kinases regulate mitotic and meiotic cell cycles, the response to polypeptide pheromones, and the initiation of nuclear DNA synthesis. The protein HRR25 from the budding yeast Saccharomyces cerevisiae was defined by the mutation hrr25-1. This mutation resulted in sensitivity to continuous expression of the HO double-strand endonuclease, to methyl methanesulfonate, and to...
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