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Article

CK2 inhibition induced PDK4-AMPK axis regulates metabolic adaptation and survival responses in glioma.

Experimental cell research - 15 May 2016

Dixit Deobrat, Ahmad Fahim, Ghildiyal Ruchi, Joshi Shanker Datt, Sen Ellora

Abstract excerpt

Understanding mechanisms that link aberrant metabolic adaptation and pro-survival responses in glioma cells is crucial towards the development of new anti-glioma therapies. As we have previously reported that CK2 is associated with glioma cell survival, we evaluated its involvement in the regulation of glucose metabolism. Inhibition of CK2 increased the expression of metabolic regulators, PDK4 and AMPK along with...

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Identifiers

PMID: 27001465
DOI: 10.1016/j.yexcr.2016.03.017

Genes

PDK4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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