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Article

Effect of glycolysis inhibition by miR-448 on glioma radiosensitivity

19 Apr 2019

Abstract excerpt

OBJECTIVE: Although glucose metabolism reengineering is a typical feature of various tumors, including glioma, key regulators of glycolytic reprogramming are still poorly understood. The authors sought to investigate whether glycolysis inhibition by microRNA (miR)-448 increases radiosensitivity in glioma cells. METHODS: The authors used glioma tissue samples from glioma patients, cells from glioblastoma (GBM)...

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PMID: 31003211
DOI: 10.3171/2018.12.jns181798

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