Article
Association of thymidylate synthase polymorphisms with the tumor response to preoperative chemoradiotherapy in rectal cancer: a systematic review and meta-analysis.
The pharmacogenomics journal - 1 Jun 2017
Yang Y C, Wu G C, Jin L, Wang K L, Bai Z G, Wang J, Zhang Z T
Abstract excerpt
Preoperative chemoradiotherapy (pCRT) followed by surgery is currently the standard therapy for patients with locally advanced rectal cancer. It is very important to develop biomarkers to prior identify the patients who have a higher likelihood of responding to pCRT. Recently, a series of studies have been conducted to investigate the association of thymidylate synthase (TYMS) polymorphisms with the tumor...
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