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Article

MTHFR C677T Polymorphism is Associated with Tumor Response to Preoperative Chemoradiotherapy: A Result Based on Previous Reports.

Medical science monitor : international medical journal of experimental and clinical research - 12 Oct 2015

Zhao Yue, Li Xingde, Kong Xiangjun

Abstract excerpt

BACKGROUND: Preoperative chemoradiotherapy (pRCT) followed by surgery has been widely practiced in locally advanced rectal cancer, esophageal cancer, gastric cancer and other cancers. However, the therapy also exerts some severe adverse effects and some of the patients show poor or no response. It is very important to develop biomarkers (e.g., gene polymorphisms) to identify patients who have a higher likelihood...

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Source

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Identifiers

PMID: 26456456
DOI: 10.12659/MSM.895433
PMCID: PMC4608643

Genes

MTHFR
EGFR
TRG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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