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Article

Thymidylate synthase gene polymorphism affects the response to preoperative 5-fluorouracil chemoradiation therapy in patients with rectal cancer.

International journal of radiation oncology, biology, physics - 1 Nov 2011

Hur Hyuk, Kang Jeonghyun, Kim Nam Kyu, Min Byung Soh, Lee Kang Young, Shin Sang Joon, Keum Ki Chang, Choi Junjeong, Kim Hoguen, Choi Sung Ho, Lee Mi-Young

Abstract excerpt

PURPOSE: This study aims to correlate thymidylate synthase (TS) gene polymorphisms with the tumor response to preoperative 5-fluorouracil (5-FU)-based chemoradiation therapy (CRT) in patients with rectal cancer. METHODS AND MATERIALS: Forty-four patients with rectal cancer treated with 5-FU-based preoperative CRT were prospectively enrolled in this study. Thymidylate synthase expression and TS gene polymorphisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20932673
DOI: 10.1016/j.ijrobp.2010.06.049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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